Abacavir and cardiovascular risk

Abacavir and cardiovascular risk.

PURPOSE OF REVIEW This review focuses on current studies addressing the association of abacavir (ABC) therapy and myocardial risk in HIV-infected patients, discusses potential pathogenetic mechanisms, and suggests a preliminary algorithm for decision making regarding ABC therapy in daily clinical practise. RECENT FINDINGS The D:A:D study was the first to reveal an increased rate of myocardial...

Abacavir and cardiovascular disease: A critical look at the data.

Most HIV-infected subjects will receive a treatment regimen including abacavir or tenofovir. Therefore, clarifying if there is an increased risk of acute myocardial infarction (AMI) among those exposed to abacavir is of the utmost importance. Due to the low frequency of AMI in this young population (2-5 per 1000 patients/year), efforts to clarify this have been quite controversial. While some o...

androgen deprivation therapy and cardiovascular risk

Knowledge and Attitude on Cardiovascular Disease Risk Factors and Their Relationship with Obesity and Biochemical Parameters

Background: According to the high prevalence of cardiovascular diseases (CVDs) in developing countries as well as high treatment expenses for patients and health-care systems, CVDs prevention in such societies has a great importance. One of the most effective strategies is improvement of knowledge and attitude towards the CVDs risk factors. This study aimed to evaluate the knowledge and attitud...

Cardiovascular risk factors and cardiovascular risk assessment in professional divers.

BACKGROUND The professional diver's activity implies body cardiovascular stress. Little data on cardiovascular risk factors is available. Some studies report a high prevalence of tobacco consumption. The purpose of this study is to investigate the cardiovascular risk factors of professional divers and calculate the predicted 5-year risk and the predicted 10-year risk of an acute coronary event....